FAQ

Frequently Asked Questions

Everything you need to know for confident, comfortable screening from home

What does Colosafe® detect?

Colosafe® detects altered DNA from colorectal cancer cells that naturally shed into your stool. This advanced DNA technology can identify cancer markers early, often before symptoms develop.

How does the test work?

The test uses a highly sensitive laboratory method called polymerase chain reaction (PCR) to detect hypermethylated syndecan-2 (SDC2) DNA in a stool sample. A positive result is returned if SDC2 methylation is detected, indicating a higher risk of bowel cancer.

Who is the test for?

Colosafe® is recommended for adults at average risk of bowel cancer, those with a family history of the disease, or anyone experiencing symptoms that concern them.

Where can I order Colosafe®?

Healthcare professionals can now order Colosafe® directly from Eurofins Biomnis. To place an order, please visit our How To Order page or contact Eurofins Biomnis at sales@ctie.eurofinseu.com

What are the risks?

Colosafe® is non‑invasive and there are no physical risks from collecting a small stool sample at home. As with any screening test, false positives and false negatives can occur. A positive Colosafe result should be followed by colonoscopy.

What does a positive result mean?

A positive result means DNA changes have been detected that require further investigation. Your doctor will receive your results and will discuss the recommended next steps with you, which typically involves a follow-up colonoscopy.

What does a negative result mean?

A negative result provides 99.8% confidence that you don't have bowel cancer¹. We recommend retesting every 2-3 years to maintain your peace of mind.

How do I prepare for the test?

No preparation needed. Just follow the simple instructions in the kit received from your healthcare professional when you're ready to collect your sample.

Frequently Asked Questions

Sample Collection Guide

References